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You must inform your healthcare provider if you have the following: Type 1 diabetes, because tirzepatide is not a substitute for insulin

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Clinical trials have shown that GLP-1 medications like semaglutide and tirzepatide can reduce body weight by 15% to 22% over the course of treatment

A condition with accessory heart electrical pathway that leads to a pre-excitation condition that can predispose individuals to arrhythmias