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Wear appropriate personal protective equipment including gloves, lab coat, and protective eyewear Handle research compounds within approved laboratory workspaces or controlled preparation areas Avoid inhalation, ingestion, or direct contact with skin and mucous membranes Dispose of unused materials and consumables according to institutional chemical waste procedures Maintain accurate labeling and documentation for all stored research compounds Following established laboratory safety protocols supports responsible chemical handling and regulatory compliance within research environments

The well-known geriatrician-haematologist Larry Solomon, working at Yale University in the USA, wrote 20 years ago: if I had treated only those people who actually had too low serum B12 and elevated MMA values, then I would not have treated approximately two-thirds of the people with a favourable response to B12 supplementation (note: partly via injections, partly via oral supplementation)

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