Oxidative stress may result in the reduction and degeneration of Leydig cells as well as a decline in their ability to synthesize testosterone, which is essential for optimal spermatogenesis 67
Dietary supplementation restored performance on spatial memory (Morris water maze) and temporal memory tasks, reduced oxidative damage to RNA in the hippocampus, and reversed age-associated mitochondrial structural decay
The most clinically serious rare side effects are acute pancreatitis, gallbladder disease, and severe allergic reactions
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One of the most serious concerns is dehydration , which can lead to acute kidney injury (AKI)
Caution Caution should be exercised