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In this study, the semaglutide-metformin combination showed that although no significant difference was observed in overall weight loss between the semaglutide-intensified and standard treatment groups, BMI, waist circumference, hip circumference, and body fat percentage were significantly lower in the semaglutide-intensified group

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Semaglutide is generally the more affordable and widely available choice, while tirzepatide costs more but may deliver stronger results for some patients

Balanced meals reduce cravings and support stable energy, hormone health, and appetite regulation

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