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When taken by mouth, stomach acid breaks down most of the peptide before it can be absorbed into the bloodstream
Nature 2016;532:255-8
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For example, glucose is the main substrate that photoreceptors utilize to create ATP in vivo 12 , but they can oxidize lipids, lactate, and use amino acids, fatty acids (such as palmitate) and other intermediate substrates to produce ATP, especially under glucose-deprived conditions 10,11,12
Distinguishing between firmly established tissue-level propagation and emerging associative models is important for maintaining interpretive balance, particularly as the field moves toward claims of systemic ferroptotic contagion
