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doi: 10.1172/JCI74915 85 MaidaAZotaASjbergKASchumacherJSijmonsmaTPPfenningerAet al

Using random forest regression as the predictive model, we identified pathways commonly associated with NRF2, such as reactive oxygen species (ROS) and xenobiotic metabolism, in addition to reduced glutathione and NADP levels, as top features associated with NRF2 dependency (Fig

Brigelius-Floh R, Floh L

The antioxidant properties of glutathione are crucial in combating the free radicals that can cause cellular damage and contribute to various diseases

Antonie Van Leeuwenhoek 58 , 8793

For quantitative variables without a normal distribution, mean and SD were substituted with median and interquartile range (IQR)