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It is sometimes used alongside insulin and other diabetes medications

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In contrast, a global pharmacovigilance study did report a significant and disproportionate association between semaglutide and reports of ischemic optic neuropathy (including NAION) [117]

Gastrointestinal side effects, such as nausea and vomiting, have been reported, along with concerns about an increased risk of intestinal obstruction and pancreatitis 11,12

Due to the limited number of studies, we decided to include various tasks and populations in the meta-analysis