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Furthermore, acitretins ability to reverse-metabolize into etretinate, particularly when combined with alcohol intake, may intensify toxicity by extending systemic exposure
Glutathione acts as an anti-oxidant by quenching reactive oxygen species, and is involved in the ascorbateglutathione cycle that eliminates damaging peroxides
No mortality was observed during the 14-week study period, demonstrating the safety of TB001 with current therapeutic dose
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