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Informed consent for brain donation was obtained from the next-of-kin of all subjects

Engs work sat largely dormant for nearly a decade, until animal studies around 1999 showed the lizard peptide improved glucose tolerance, expanded beta cell mass, and reduced food intake in rodents

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KPV, a tripeptide derived from the C-terminus of alpha-MSH, provides potent anti-inflammatory effects through NF-B inhibition independent of melanocortin receptor activation

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