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Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells

Interactions [edit] Binding partners [edit] ADP [edit] ADP binds behind the NAD-BD, just beneath the pivot helix - in the special ADP allosteric site

Y., Li, J

a second group of 20 women received a placebo

Finally, we discuss how individual variation arises and its consequences for one-carbon and glutathione metabolism

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