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B12 injections are especially beneficial for: People with pernicious anemia, an autoimmune condition destroying intrinsic factor Those with gastrointestinal disorders affecting absorption Individuals who have undergone gastric surgery or bowel resection Older adults with decreased stomach acid production Patients with severe deficiency requiring rapid replenishment Individuals who struggle with adherence to daily oral supplements Shots offer a reliable, quick way to restore B12 levels in these populations

MIC B12 injections as monotherapy produce minimal weight loss (1-2 pounds over 12 weeks, not statistically significant)

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Anti-Doping Agency warns that there is a concerning lack of published clinical trial data because studies appear to have been cancelled or stopped without any published conclusions

Compounded products do not pass through that same approval process