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Numerous factors leading to DE, such as environmental stress, blue light exposure, autoimmune diseases, metabolic disorders, and aging, are closely linked to mitochondrial disturbances
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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected
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