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If diarrhea occurs, ensure adequate hydration and electrolyte replacement
When to seek medical advice : Patients should contact their GP or prescribing clinician if nausea is severe and persistent, if they are unable to keep down fluids for more than 24 hours, if they experience severe abdominal pain, or if side effects significantly impact their quality of life
Research suggests only 20-30% of patients who discontinue semaglutide maintain their weight loss for longer than 12 months without medication
Regulation of gastroduodenal motility: acyl ghrelin, des-acyl ghrelin and obestatin and hypothalamic peptides
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Khan S et al
On average, people using tirzepatide in studies lost around 510% of their body weight during the early months, depending on the dose and lifestyle factors such as diet and physical activity
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