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J Pineal Res

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In most cases, due to the fatty infiltration of the liver, these infants will present with hepatomegaly

Malabsorption (inadequate intake of vitamin B12 in the intestine) Insufficient production of intrinsic factor (a protein that is produced in the gastric mucosa and is required for the absorption of vitamin B12), Diseases in the terminal part of the ileum (part of the small intestine), eg

IV infusion requires clinical setting Regulatory status: NMN was challenged by FDA as a supplement (2022) but remains commercially available

Zilleruelo G et al