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This work received support from the French government under the Investissements d'Avenir program, Initiative d'Excellence d'Aix-Marseille Universit via AMidex NeuroMarseille AMX-19-IET-004, and NeuroSchool ANR-17-EURE-0029 funding

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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

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