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There are no timing restrictions driven by interaction risk, no dose adjustments required because of the other compound, and no contraindicated combinations within this pairing

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Over a mean follow-up period of 39.8 months, semaglutide demonstrated superiority over placebo in reducing the composite endpoint of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke among overweight or obese patients with established cardiovascular disease, but without diabetes

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Statistical analysis Data were analyzed using SPSS ver