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Abstract Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) has emerged as a prevalent and severe global hepatic disorder, necessitating the development of effective therapeutic strategies

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The promoter of IGF-1R is CG-rich and lacks TATA and CCAAT elements (LeRoith et al, 1995b), but has elements found in housekeeping genes, containing regulatory elements characteristic for highly regulated genes (Werner et al, 1991)

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