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Therefore, it plays a crucial role in immune function, detoxification capacity and protection against oxidative stress

Loss of ER redox homeostasis can lead to ER stress and induction of the unfolded protein response (UPR) which, if severe enough will trigger cell death via the apoptotic pathway

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doi:10.1074/jbc.M509496200

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If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your healthcare provider