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DailyMed prescribing information for Wegovy lists nausea, vomiting, diarrhea, abdominal pain, constipation, dyspepsia, flatulence, gastroesophageal reflux disease, gastritis, and other gastrointestinal reactions among reported adverse reactions

Given that impaired autophagy and dysregulated mucin secretion are key contributors to barrier dysfunction, TB-500s regenerative and anti-inflammatory actions may indirectly support mucin2 production and mucus layer integrity, though direct evidence in colitis models remains limited

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