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ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway

The objective of the current study was to demonstrate the therapeutic potential of oral administration of glutathione in an open-label, single-arm, multicenter, pilot study prior to subsequent large-scale clinical trials

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Cone AS, Yuan X, Sun L, et al

Interestingly, GHK-Cu did not show any signs of irritation