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doi: 10.1212/WNL.0b013e3182563b19 6

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Additionally, the ability of GLP-1R agonists to modulate the NVU and reduce neuroinflammation suggests that they could slow the progression of neurodegenerative diseases

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Vpr induces oxidative stress by stabilizing p53 protein, increasing transforming growth factor-beta protein levels and ROS production, and suppressing antioxidant enzymes 118,119,120

Mechanism of Action 2,3 Glucagon-like peptide-1 (GLP-1) is a hormone produced and secreted in intestinal cells and in the brainstem upon food consumption