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Phase 2 detoxification is the critical step where these highly reactive intermediates are neutralized and prepared for safe excretion from the body

Marenich, A

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Patch Test Recommended: If you have extremely reactive or allergy-prone skin, perform a patch test on a small area 24 hours before full-face application

A deeper understanding of these interconnected pathophysiologic mechanisms will facilitate the development of targeted therapies beyond cysteamine, optimizing treatment approaches to mitigate disease progression [146]

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