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L., Aramburu, O., and Vazquez, C
Acta Chir Scand Suppl 1983;517:157-164
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It suppresses RNA production in 70% of 54 human genes overexpressed in cancer patients and upregulates 10 caspase and caspase-associated genes, which are crucial for programmed cell death (apoptosis) a key defense against cancer
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In the connection to inflammation, we showed that elevation of pro-inflammatory cytokine IL-6, increased anxiety at the lightdark test, and smaller hippocampal volume characterized at baseline (before any applied stress) those mice that become susceptible after social defeat stress (SDS) with social withdrawal and impaired transcriptomic-wide changes in ventral dentate gyrus, and that administration of LAC promoted behavioral resilience at the SDS paradigm in this susceptible phenotype [27]
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