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In NOZ cells, acylcarnitine upregulates m6A methylation levels in a dose-dependent manner by decreasing the expression of ALKBH5 and increasing the level of METTL3, thereby stabilizing lncBCL2L11 expression [44]

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Here, we critically evaluate and discuss advances in development of currently reported transporter-utilizing (pro)drugs and nanocarriers in light of the main CNS pharmacokinetic principles