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Furthermore, adding sodium bicarbonate to buffer local anesthetic solutions like lidocaine and bupivacaine can reduce injection pain by increasing pH, enhancing anesthetic effectiveness

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The incretin effect is significantly blunted in type 2 diabetes mellitus (T2DM) and restoration of this incretin signalling could be effective as a treatment strategy for diabetes, obesity and metabolic dysfunctions [5, 6]

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Trevenzoli M, Cattelan AM, Marino F et al: Sepsis and granulomatous hepatitis after bacillus calmette-guerin intravesical installation