Researchers have questioned the effectiveness of glutathione supplementation due to its low bioavailability
The oxidative stress caused by a decrease in GSH levels can then impact microglia function and potentially lead to a more pro-inflammatory M1 phenotype that has reduced -amyloid clearance capabilities (Vilhardt et al., 2017)
Additionally, B12 from injections is released more gradually throughout the body, providing longer-lasting effects
To, K., Cao, R., Yegiazaryan, A., Owens, J., Nguyen, T., Sasaninia, K., Venketaraman, V
Microbiome 6, 133
Glutathione peroxidase (GPx) activity at a fixed concentration of 300 U/L was used to evaluate the modified DTNB-GPx method