Dermal pigmentation (deep melasma, lichen planus pigmentosus, drug-induced pigmentation) is located in the deeper dermis it does not respond to surface peels and requires NCFT, exosome therapy or intradermal mesotherapy to reach the melanocytes
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2 5 This research is real and interesting, and it is the intellectual engine behind claims that GHK-Cu resets cells toward a healthier, more youthful pattern
For example, it reacts with the NO radical, and makes toxic peroxynitrite
Cell Physiol 311 , C537C543 (2016)