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This provides long fasted periods potentially enhancing insulin sensitivity and fat oxidation
Covers exenatide, semaglutide, tirzepatide, oral Wegovy, retatrutide, CagriSema, and the evolution from diabetes to obesity treatment.
This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide)
The MTHFR gene (methylenetetrahydrofolate reductase) is responsible for converting folate into its active form, methylfolate
The MHRA has approved various GLP-1 agonists for specific indications, with NICE providing guidance on their use in type 2 diabetes (NG28) and weight management (TA875 for semaglutide/Wegovy, TA664 for liraglutide/Saxenda)
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