eli lilly clinical trials tirzepatide New trial: Zepbound (tirzepatide) helped adults lose an average of 20.2% of their body weight—around 50 lbs—over 72 weeks, outperforming Wegovy's 13.7% (~33 lbs). Credit to: https://www.healthline.com/health-news/zepbound-wegovy-weight-loss A Study of Investigational Tirzepatide

However, recruitment challenges highlight potential barriers to scaling similar interventions, particularly in populations with varying degrees of health or cognitive impairment

Dextrose infusions are administered to provide calories and limit ketosis

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Even more concerning, girls and mothers have told me they are turning to GLP-1s for shidduchim, to quickly lose weight before dating or a simcha, to appear more desirable to a partner, or simply to meet community and family expectations about body size

Probucol, a lipid-lowering agent, also exhibits antioxidant properties that reduce intracellular oxidative stress and maintain normal cellular redox state by upregulating Nrf2 and GPX4 protein expression, thereby enhancing cardiomyocyte antioxidant capacity