Two studies on DDI between GLP1RAs and COCs enrolled post-menopausal women [17, 18] and three studies enrolled pre-menopausal women [14, 15, 21]
Semaglutide creates a broader metabolic shift by signaling satiety directly, reducing hunger hormones, and improving how your digestive system processes food
However, our clinical experience indicates otherwise
Discontinuation or dose reduction of semaglutide is recommended rather than relying solely on symptomatic treatment of volume depletion
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In the general population prescribed GLP-1s, stopping the medications comes with a rebound in weight gain and related metrics, such as blood pressure, cholesterol and blood sugar