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Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans

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doi: 10.1016/j.nbd.2018.06.001 205 ZhangHWenMChenJYaoCLinXLinZet al

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Greater improvements in participants with exenatide plus dapagliflozin may be explained in part by their different, and potentially complementary, mechanisms of action and confirm other studies showing that combining these two agents may exert stronger beneficial effects than each drug alone, Karen Elkind-Hirsch, MSc, PhD, HCLD , scientific director of research at Womans Hospital Research Center in Baton Rouge, Louisiana, told Healio

Use appropriate syringes and needles (typically 4-6mm length, 31-32 gauge for subcutaneous delivery)