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Food and Drug Administration Park, J., et al
Their effects are more often reflected in symptom improvement rather than lab results
In PIONEER 8, patients whose insulin dose was increased by 20% during treatment were considered to have required rescue medication
With over 14 years of clinical trial data and 7 years of real-world use, semaglutide represents one of the more thoroughly studied medications in its class, though it's important to recognize that very long-term data (beyond 57 years of continuous use) remains limited
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