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The final weeks maintain the tissue signaling environment while injection frequency reduces

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oIGF-1 at a concentration of 10 ng mL 1 in DMEM increased myoblast proliferation by 22% compared to DMEM alone ( p = 0.045 by post hoc analysis) (Figure 2)

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The direct comparison between semaglutide and dulaglutide represents a major strength of this study

Both groups received current standard of care, including CV risk factor management and individualized healthy lifestyle counseling (including diet and physical activity)