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Taken together, the vegetarians investigated in this study had different degrees of vitamin B-12 deficiency, which were related to the degree of animal product restriction

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Antibiotic use, chronic stress, and certain medications can also reduce the population of butyrate-producing bacteria in the colon

Some studies have also proposed that TNF modulates the Rho GTPase pathways regulating the cytoskeleton through the activation of the autophagy pathway, providing a link to a stress response 42,43,44