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Pharmacokinetic parameters such as AUC, maximum plasma concentration (Cmax), terminal elimination t1/2, volume of distribution (Va), and clearance were calculated [1]

Future clinical validation, particularly in diverse populations considering genetic, metabolic, and environmental factors, is necessary to confirm these computational findings

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The condition develops gradually, often over months or years, as the body's B12 stores become depleted

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The signaling and structural work attributed to GHK-Cu depends on the intact chelate reaching target tissue, not the copper alone