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There is every reason to argue that the efficacy observed for compounds 1 and 2 in vivo incorporates a similar role for the host immune response as seen for other schistosomicidal agents

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The mechanism of action involves several physiological effects: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, helping to lower blood glucose levels without causing hypoglycaemia when glucose levels are normal

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The WADA Prohibited List is revised on an annual basis, with each update published in October and taking effect January 1 of the following year

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