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In addition to ROS overproduction, the activation of MAPK and inactivation of phosphatidylinositol 3-kinase/Akt (a serine/threonine kinase that is also known as protein kinase B)/mammalian target of rapamycin (mTOR) are associated with both apoptosis and autophagy 6

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81401852), the Natural Science Foundation of Shanghai (No

Off-label use involves prescribing a medication for a medical reason that does not have approval from the FDA

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