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The central dopamine and prolactin levels plays a key role in the glucose homeostasis control, and their dysregulation could lead to the pathognomonic central insulin resistance depicted in the ominous octet

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The dual GLP-1/GIP mechanism creates potent metabolic effects at lower doses than single-target agonists

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It is a dual agonist that activates both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors simultaneously

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