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To determine the NMR-derived K D estimations of 1907 at each FAT binding site, we integrated the peak areas of key residues important for LD2 binding at each site and plotted change in integration area as a function of 1907 concentration (Fig
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243 The TAMs are immune cells that exhibit immunosuppressive functions, and reducing TAMs infiltration can inhibit tumor growth and improve survival rate
Bally MB, Mayer LD, Loughrey H, Redelmeier T, Madden TD, Wong K, et al
Klapheck et al., 1994)
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