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Note additionally that the three methionine residues in the sequence, two of them in the N-terminal extension, make dilute standing solution vulnerable to oxidation, and that freeze-thaw cycling promotes aggregation in disulfide-bonded proteins more readily than in short peptides

Nature Communications 9 , 1410, (2018)

PMID: 26884697

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The regulatory framework for workplace testing, established by SAMHSA guidelines, does not include peptides and shows no movement toward including them

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