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Further, comparing the overall structure of the mature and T391A precursor of EcGGT demonstrated that backbone atoms in the core regions of both the proteins remain unchanged, while significant conformational changes occurred proximal to the active site (Okada et al., 2007)

doi: 10.1016/j.exer.2025.110601 185 WangYLiPWangCBaoSWangSZhangGet al

PMID: 21356520

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Some trials report significantly reduced oxidative markers versus a control group, though results vary by dose, route, and baseline levels