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healthcare providers oversee the prescription and management of leading GLP-1 therapies, including Semaglutide (Wegovy, Ozempic) and Tirzepatide (Mounjaro, Zepbound)

The ceiling dose is 1.0mg daily exceeding this provides no proportional increase in melanogenesis but significantly increases off-target melanocortin receptor activation

Symptoms may include dizziness or lightheadedness, blurred vision, mood changes, sweating, slurred speech, hunger, confusion, drowsiness, shakiness, weakness, headache, rapid heartbeat, or feeling jittery

Instead, a historical cohort study of over 200,000 electronic health records found a reduced association between semaglutide use and suicidality in both people with T2DM and obesity at 1 year 209