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Furthermore, increased ACE2 expression in alveolar type II pneumocytes and alveolar macrophages of individuals with severe SARS-CoV-2 disease (ARDS with diffuse alveolar damage) requiring mechanical ventilation (Baker et al., 2021) favors a concomitant increase in oxidative stress in those individuals

FIGURE 2 The binding mode of compound 102 was predicted by molecular docking studies ( Figure 2D )

This step is very important for the right dose

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Statistical analyses All analyses were completed with GraphPad Prism7 Software (San Diego, CA, USA)

However, it is also suggested that the reduced state of GSH in predominance protects the activity of the main enzymes of photosynthesis 36