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Incubation with 13 C 3 -serine as an extracellular serine source for 6 h resulted in almost complete labeling of the intracellular serine pool (Fig
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The wide range of synaptic deficits observed in ASD-associated SHANK3 rodent models are alterations in NMDARs [72]
Bucur MP et al
Angle the needle against the inner wall of the vial and push the plunger slowly
Several factors have been identified related to the pathogenesis of ALS: OS, mitochondrial dysfunction, neuroinflammation, excitotoxicity due to an increase in the neurotransmitter glutamate, defect in axonal transmission and in the metabolism of RNA, apoptosis, cytoskeletal abnormalities, disruption of membrane trafficking, endoplasmic reticulum stress, protein misfolding and aggregation (Papadimitriou et al., 2010
