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A 2025 meta-analysis found tirzepatide (the drug in Mounjaro and Zepbound) lowered inflammation markers hsCRP by about 33% and IL-6 by about 18% versus placebo

(Keep reading to find out why.) Are peptides effective

doi: 10.3390/biom13091332 Summary Keywords GLP-1 receptor agonists, Sepsis, muscle atrophy, inflammation, oxidative stress Citation Dimic N, Djuric M, Vejapi M, Nenadic I, Bobos M, Bojic S, Savic P, Milanovic M and Stevanovic P (2025) The role of GLP-1 in the pathophysiology and treatment of sepsis: a narrative review

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As per the agreement, Merck will pay $112 million upfront, while pledging up to $1.9 billion in development, regulatory and commercial milestones