ROS accumulation mediated by FGF23 worsens Ca 2+ influx and PS exposure, thereby promoting faster erythrocyte removal (Mehta et al., 2017)
It's the reason an Indian man with BMI 23 can have the metabolic profile of a European man with BMI 30
GLP-1 has very significant glucagon suppressive effects at normal plasma glucose levels and at elevated plasma glucose levels
Some of the most important medicines we already have are peptides: Insulin has kept people with diabetes alive for a century, and semaglutide is the blockbuster of the decade
They act on completely different receptor pathways to produce the same end result (growth hormone release)
Protein Eating enough protein helps to keep you full and satisfied for longer, in part because protein increases the release of GLP-1, as well as another satiety influencing hormone (peptide YY, or PYY)