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Obesity and HFD are associated with perturbations in bile acid homeostasis, including increased hepatic bile acid synthesis and altered circulating and intestinal bile acid profiles (82)
Its real-world benefit is conditional strongest in vegetarians, vegans, and physically active individuals, and weak to negligible in sedentary people with already-sufficient carnitine status
While safety was established, efficacy for weight loss did not meet clinical trial success criteria
Metabolism Intestinal absorption Biliary and pancreatic secretions are needed in the small intestine for fat digestion
& Kimble, J
Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation
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