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Ageing and neuronal vulnerability
Constipation: Duration data is less well-characterized, but clinical experience suggests constipation may persist longer than other GI side effects, sometimes requiring ongoing management strategies throughout treatment
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This appears to contribute to its resistance to fungus, with GSNO after infection being exclusively redistributed to the epidermal cells which are usually this pathogen's penetration sites in sunflowers (Chaki et al., 2009)
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