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Although you can increase your GLP-1 naturally, levels stay high for a longer time when you take medications to increase GLP-1

Average weekly loss: 0.51.5 kg (13 lbs) Average monthly loss : 26 kg (413 lbs) Results vary based on dose, lifestyle, starting weight, and metabolic health Average weekly loss ranges from 0.251 kg (0.52 lbs) for most patients, with higher early losses possible in some individuals

Finally, there is a risk of malnutrition for older adults on GLP-1s

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For example: Endogenous GHRH has a half-life of ~515 minutes Native GLP-1 is broken down in under 2 minutes Thats why natural peptides are rarely used directly in therapeutics theyre too unstable

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