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But knowing when to stop or seek help is essential for safe use

The primary mechanism of action is likely due to activation of vagal afferent nerves that innervate the stomach and direct binding to GLP-1 receptor on gastric mucosal cells leading to delayed gastric emptying

They are not as bioavailable because they become metabolized in passing through the stomach

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Trusted Source Tirzepatide as a novel effective and safe strategy for treating obesity: A systematic review and meta-analysis of randomized controlled trials

This study does not require ethical review or approval but must comply with relevant laws and regulations